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Diagnosis of Rheumatoid Arthritis
Immunologic blood tests demonstrate abnormalities of the immune system. Immunity to disease depends on the body's ability to produce antibodies (immunoglobulins) when challenged by foreign substances (antigens). Antibodies bind to and help eliminate antigens from the body. The inability of the body to produce certain classes of immunoglobulins (IgG, IgA, IgM, IgD, IgE) can lead to disease. Complexes formed by the antigen-antibody reaction can be deposited in almost any tissue and can lead to malfunction of that organ. Immunofluorescence assays to detect antinuclear antibodies (antibodies that will bind to antigens within the nucleus) can be used to diagnose systemic lupus erythematosus and rheumatoid arthritis
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