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Chronic Lung Disease

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Chronic Lung Disease

There are at least three reasons why the lungs are particularly liable to be involved in allergic reponses to proteins. First, the lungs are exposed to the outside environment, and hence particles of foreign protein—e.g., in pollen—may be deposited directly in the lung; second, the walls of the bronchial tree contain smooth muscle that is very likely to be stimulated to contract if histamine is released by cells affected by the allergic reaction; and third, the lung contains a very large vascular bed, which may be involved in any general inflammatory response. It is therefore not surprising to find that sensitivity phenomena are common and represent an important aspect of pulmonary disease as a whole. The most common and most important of these is asthma. This word is loosely applied to all kinds of conditions in which there is airflow obstruction, but it is better reserved for those conditions in which an allergic component of the bronchial obstruction is likely to be present.

Article ID: 88
Word Count: 178
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