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Home » Depression » Cause of Depression
Depression can have many causes. The loss of one's parents or other childhood traumas and privations can increase a person's vulnerability to depression later in life. Stressful life events in general are potent precipitating causes of the illness, but it seems that both psychosocial and biochemical mechanisms can be important causes. The chief biochemical cause seems to be the defective regulation of the release of one or more naturally occurring monoamines in the brain, particularly norepinephrine and serotonin. Reduced quantities or reduced activity of these chemicals in the brain is thought to cause the depressed mood in some sufferers.
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